Slow Cooker Mac & Cheese Stuffed Meatloaf is the mouthwatering dinner you didn’t know you needed! It just doesn't get any better than this delicious twist on two classic comfort food favorites. Rich, cheesy macaroni surrounded by juicy, seasoned meatloaf.
*This is an updated and improved version of a recipe that was originally posted 9/2020.

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Yes - you read that right! Macaroni and cheese stuffed inside meatloaf is a thing. An amazingly delicious thing! And much easier to make than you might think.
The best part? Your crockpot babysits it for you and delivers big flavor and cheesy wonderfulness. Your whole family will thank you for making this delicious recipe.
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📝Shopping list
These are the ingredients you’ll need to make this cheese meatloaf casserole. For exact measurements and full preparation instructions, please see the recipe card at the bottom of this page.
- Extra lean ground beef - the leaner the better. Beef with a higher fat content will give you a greasier meatloaf. To keep things extra lean, I often opt for a combo of โ ground turkey with โ ground beef.
- Eggs
- Panko bread crumbs I use seasoned bread crumbs
- Ketchup see below for substitution options
- Dried onion flakes, garlic powder, salt & pepper
- Frozen prepared macaroni & cheese I use Stauffers, but go with your favorite!
- Mozzarella and sharp cheddar cheese shredded
💜Why use your crock pot for this recipe
- Slow Cooker Convenience - Set it and forget it. No oven required!
- Make-Ahead Friendly - Assemble it in the morning, and it's ready in time for dinner. The meat mixture for this juicy meatloaf can be mixed and stored overnight in the refrigerator.
- Moisture and Tenderness - Slow cookers trap steam and cook at a low, steady heat, which helps keep the meatloaf incredibly moist and tender.
- Keeps Food Warm for Serving -Once it’s done, just switch your crockpot to the warm setting, and it’ll stay hot and ready until dinnertime. Perfect for late nights, potlucks, and kids' birthday parties.
🎥Watch how to make it
Preparing Your Slow Cooker
Prep your slow cooker for macaroni and cheese-stuffed meatloaf by coating it with a non-stick agent. Any non-stick spray or oil will work. Olive oil and avocado oil are my go-to coatings.
NOTE: Some slow cooker inserts come with a nonstick surface. Use of a non-stick agent is still suggested. However, oil is sometimes recommended rather than spray to protect the longevity of the non-stick surface. Check your slow cooker's manual if you have any concerns.
Alternatively, use a liner to make this slow cooker meatloaf recipe cleanup even easier.
Cooking
- 🍽️Place meat, seasonings, eggs, bread crumbs, and ketchup into a large bowl and mix to fully combine.
- 🍽️Add about โ of this meat mixture to a greased slow cooker. Use your hands to flatten evenly along the bottom of the slow cooker and about 2" or so up the side wall - all the way around.
- 🍽️Place frozen macaroni and cheese in the center of the loaf mixture. If you can't fit it in nicely, use a knife to cut it into pieces and fit it in like a puzzle
- 🍽️Use shredded cheese to fill in gaps around the frozen chunks of mac and cheese. Top the mac and cheese with remaining cheese.
- 🍽️Place the remaining meat mixture on top of the shredded cheese. Flatten it and pinch the edges with the meat coming up the side of the slow cooker. Your macaroni and cheese should be fully wrapped in a ground meat cocoon.
- 🍽️Cover and cook on low for 7-8 hours or high for about 4 hours.
Top tip
A casserole-style or oval shape slow cooker works best—avoid round cookers for this recipe.
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🍽Serving suggestions
This stuffed meatloaf pairs perfectly with:
- Garlic bread (great for scooping up that cheesy filling!)
- Steamed green beans or broccoli
- Cole slaw
- A crisp garden side salad
- Baked or mashed potatoes
If you love this recipe...
Please let me know in the comment section below!
🔁Substitution ideas
- Not a fan of ketchup? Use your favorite bbq sauce instead.
- Looking to add a little heat? Use spicy ketchup. Red pepper flakes are also a great way to dial up the heat.
- Freshly diced onion and minced garlic are great in place of dried. Onion powder can also be used in place of flakes.
Storing and reheating
Store crockpot meatloaf leftovers in an airtight container in the refrigerator for up to 4 days. Gently reheat individual portions in the microwave or warm larger portions in the oven at 300°F until heated through.
😉Hints and Hacks
- Is meatloaf one of your favorite comfort foods? Then you will also love this classic meatloaf recipe and Greek turkey meatloaf.
- This easy recipe is great if your people eat at different times. After cooking time, turn your slow cooker to low, and everyone can have a warm and filling meal, no matter what time they are ready to eat.
- I like to mix meatloaf with my hands so I use gloves that have been fda approved for direct contact with food. This keeps my hands clean for adding the mac n cheese filling.
- For easy clean up on busy nights, use a slow cooker liner. This is, of course, an optional step. I like to purchase my liners in bulk for a less expensive per-piece price.
- In the market for a casserole slow cooker? I love mine!
๐ Recipe
Mac & Cheese Stuffed Meatloaf
(Click on the stars to leave a rating)
Print Pin Rate SaveAll nutrition information shown here is automatically generated and should be considered an estimate. If you follow a specific diet, please calculate your own values to ensure accuracy.
Equipment
- 6 qt or larger slow cooker or a 3.5 quart casserole slow cooker. I do not recommend making this in a round slow cooker
- mixing bowls
- measuring cups and spoons
Ingredients
- 3 lbs ground beef 90% leaner or leaner
- 4 eggs
- 1 cup panko bread crumbs I use seasoned bread crumbs
- 1 cup+ ketchup
- ¼ cup dried onion flakes
- 1 tablespoon garlic powder
- 1 pinch each - salt and pepper
- 2 12oz packages frozen prepared macaroni & cheese I use Stauffers
- 1 cup cheddar cheese shredded
- 1 cup mozzarella cheese shredded
Instructions
- Place 3 lbs ground beef, 4 eggs, 1 cup panko bread crumbs, 1 cup ketchup, ¼ cup dried onion flakes, 1 tablespoon garlic powder, and 1 pinch each - salt and pepper. Mix together thoroughly. This works best using your hands!3 lbs ground beef, 4 eggs, 1 cup panko bread crumbs, 1 cup+ ketchup, ¼ cup dried onion flakes, 1 pinch each - salt and pepper
- Place about โ of beef mixture into a greased slow cooker. Flatten mixture with hands along bottom and about 2" up the sides of slow cooker so that the slow cooker is lined with your ground beef mixture.
- remove 2 12oz packages frozen prepared macaroni & cheesefrom containers and add into middle of the meat. If they don't fit side by side, you can cut or break them to fit2 12oz packages frozen prepared macaroni & cheese
- Use1 cup cheddar cheese and 1 cup mozzarella cheese to fill in any gaps and to cover mac and cheese blocks
- Add remaining beef mixture on top and use hands to make sure all mac and cheese is covered in a ground beef cocoon. Pinch together edged of top layer with the ground beef coming up the side of your slow cooker. Your mac and cheese should now covered cocoon-like in ground beef.
- drizzle top of meat mixture with ketchup
- cover and cook on low for 7-8 hours or high for about 4 hours
Final Step
If you love this recipe, please let everyone know by giving it a star rating and leaving a comment. This will help my business to grow and allow me to keep on testing and sharing free recipes with you.😊
Video
Notes
Nutrition
All nutrition information shown here is automatically generated and should be considered an estimate. If you follow a specific diet, please calculate your own values to ensure accuracy.
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Ellen says
What a wonderful idea. Must try.
Cheryl says
Can you subsitute 1 cuo of cream of mushroom soup instead of ketchup
admin says
I have never tried it with cream of mushroom soup. I do feel that the ketchup adds a great flavor, so I am not really sure how it would turn out. If you decide to try it, please let me know how it goes!
Becky says
Can you make Mac & cheese then freeze it? Instead of store bought
The Lazy Slow Cooker says
Hi Becky, I donโt see any reason why you couldnโt freeze homemade mac & cheese and use it in this recipe! How do you make your mac and cheese? Do you make it in your slow cooker?
Thanks for asking...I hope this helps!